The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms
Fig 4
The effect of 9 agonists on Tsu-ACR-16-like receptor.
Representative sample traces and a bar chart (mean ± SEM) show the rank order potency series of 4 cholinergic anthelmintics: oxantel (oxa), pyrantel (pyr), morantel (mor), levamisole (lev) and 5 nAChR agonists: epibatidine (epi), nicotine (nic), 3-bromocytisine (3-bc), dimethylphenylpiperazinium (DMPP) and cytisine (cyt). P < 0.05; significantly different as indicated; Turkey’s multiple comparison test.