SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts
Fig 5
Cytokinemia during SARS-CoV-2 infection.
Cytokines were measured in longitudinal plasma samples using the Cytokine & Chemokine 30-Plex NHP ProcartaPlex Panel from Invitrogen. (A) MCP-1; (B) IL-1RA; (C) IP-10; (D) ITAC/CXCL11/IP-9; (E) BLC/CXCL13; (F) Eotaxin; (G) SDF-1. Parameters not shown were below the limit of detection across all animals and time points. Aerosol (closed symbols/solid lines; n = 4); multi-route mucosal (open symbols/dashed lines; n = 2). A 2-way ANOVA with multiple comparisons was used to determine statistical significance compared to 0 dpi and is indicated by asterisks above each time point. N.s. in the lower right corner indicates no significant differences.