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COVID-19 pandemic: Insights into structure, function, and hACE2 receptor recognition by SARS-CoV-2

Fig 2

Phylogenetic relationships in the Coronavirinae subfamily.

The subfamily is formed by 4 genera: Alphacoronavirus, Betacoronavirus (lineages A, B, C, and D), Gammacoronavirus, and Deltacoronavirus. We randomly picked 62 SARS-CoV-2 genome sequences, representing 15 different countries, together with other Coronavirinae subfamily members. The phylogenetic tree was created using NgPhylogeny.fr tool. The analysis indicates that SARS-CoV-2 has a close relationship with bat coronavirus RaTG13 and SARS-CoV; therefore, it is classified as a new member of the lineage B Betacoronavirus. SARS-CoV, Severe Acute Respiratory Syndrome Coronavirus; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus-2.

Fig 2

doi: https://doi.org/10.1371/journal.ppat.1008762.g002