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Lymph nodes—The neglected battlefield in tuberculosis

Fig 2

Mtb infection results in granuloma formation that disrupts the normal lymph node architecture.

(A) Lymph node showing normal architecture without granuloma formation. (B) Lymph node with partially effacing granulomas. (C) Total nodal effacement by multiple coalescing non-necrotizing granulomas. (D) Near total nodal effacement by multiple coalescing caseous granulomas. Granulomas are outlined with a white line. Measuring bar = 1 mm. Mtb, Mycobacterium tuberculosis.

Fig 2

doi: https://doi.org/10.1371/journal.ppat.1008632.g002