An improved animal model for herpesvirus encephalitis in humans
Fig 5
Viral antigen score in mice infected with mutant viruses.
Histological specimen of mice infected with PrV-Ka (A), PrV-US3Δkin (B), PrV-ΔUL21 (C) and PrV-ΔUL21/US3Δkin (D) were scored for viral antigen distribution with negative (0), focal to oligofocal (1), multifocal (2) and diffuse (3). The final average value resulted from points given for each tissue section analyzed. Significant differences of mutant viruses compared to the mock-infected control group are indicated with an asterisk (*).