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Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent

Fig 14

Modelling of K. pneumoniae Sel1E.

(A) Sequence alignment between Sel1D and Sel1E showing the residues (green) that are both variable and predicted to be exposed by ConSurf. (B) MODFOLD residue accuracy prediction for the Sel1E I-TASSER model. The colour scheme for the accuracy (Å): blue (high accuracy) through green, yellow and orange to red (low accuracy). (C) Electrostatic surface potentials for Sel1E. The close-ups show the variable residues (green; marked by an asterisk in (A), which contribute to the unique electrostatic potential surface of Sel1E, see text for more details. Due to the low confidence of the C-terminal part of the model, only the region of high confidence was used for the comparison. The electrostatic surfaces were calculated with the APBS tool (Adaptive Poisson–Boltzmann Solver) in PyMOL and the colour ranges from -7 to 7.

Fig 14

doi: https://doi.org/10.1371/journal.ppat.1007969.g014