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Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment

Fig 5

World map showing proportion of resistance and sensitive alleles in South America (Brazil), West Africa (Senegal and Niger), East Africa (Tanzania) and Middle East (Oman).

Number of homozygous (hmz) and heterozygous (htz) parasites for resistance alleles, and total number of parasites sampled (N) are shown below the pie charts. East Africa showed the highest frequency of resistance alleles and resistant parasites. Data from Brazil from a previous study [13] was added for comparison.

Fig 5

doi: https://doi.org/10.1371/journal.ppat.1007881.g005