Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells
Fig 2
The relative abundance of individual cellular mRNAs in the cytoplasm and on polysomes decreases between 2 and 6 hpi.
(A) Scatter plots of Transcripts per Kilobase Million (TPM) for exonic regions at 2 hpi. The TPM in uninfected cells for a given mRNA is graphed on the abscissa, and the TPM for a given cellular mRNA in either uninfected (black circles), or VSV infected cells (gray circles) is graphed on the ordinate. The viral mRNAs are indicated by the red triangles. (B) Density plots of the log2 fold change in TPM for cellular mRNAs between uninfected or VSV infected cells at 2 hpi. C, M, and P denote “cytoplasm”, “monosome”, and “polysome”, respectively. (C) Scatter plots of TPMs for individual mRNAs at 6 hpi, presented as in A. (D) Density plots of the log2 fold change in TPM at 6 hpi, presented as in B.