A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici
Fig 5
Comparison of Z. tritici 3D models of the two SQR paralogs and putative binding modes for SHA SDHIs.
(A) Homology model of Z. tritici WT-SQR (blue) superimposed on the homology model of Z. tritici altC-SQR (salmon). (B) Putative binding mode of pydiflumetofen in Z. tritici WT-SQR. (C) 2D depiction of SDH inhibitors used for docking comparisons and discussed in the text. (D) Putative binding mode of isofetamid in Z. tritici WT-SQR. E. superposition of energy minimum conformations for pydiflumetofen and compound 3.