A model of chronic, transmissible Otitis Media in mice
Fig 7
Adaptive immune components contribute to controlling B. pseudohinzii colonization in the middle ears of mice.
Numbers of B. pseudohinzii recovered from wild type (C57BL/6J) and B-cell (MuMt-), T-cell (Tcratm1Mom), and B/T-cell (Rag-/-) deficient mice 49 days following inoculation with 7500 CFU delivered to the external nares in 25 μl of PBS. Error bars indicate standard deviation. Arrows indicate the contributions the adaptive immune components have on controlling colonization levels. One-way Anova with Dunnet’s post-test was used to determine statistical difference compared to wild-type: † = p-value <0.1, * = p-value <0.05, ** = p-value<0.002.