A model of chronic, transmissible Otitis Media in mice
Fig 5
Colonization of mice by B. pseudohinzii following experimental inoculation or natural transmission.
A.) Colonization profiles of B. pseudohinzii in the nasal cavity, trachea, lungs and middle ears of C57BL/6J mice experimentally inoculated with B. pseudohinzii (5 CFU in 5 μl) and analyzed on days 1, 3, 7, 21, 49, and 98 days post inoculation (n = 3 per group). Error bars indicate standard deviation. Dashed line indicates the limit of detection. B.) Mice colonized via natural transmission when co-housed for 28 days with experimentally inoculated mice. Colonization profiles for the individual mice are shown in the lower graphs (NC: nasal cavity, TR: trachea, LNG: lungs, RE/LE: right and left middle ear bullae).