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Full restoration of specific infectivity and strain properties from pure mammalian prion protein

Fig 5

Regional neuropathology of M109 cofactor recPrPSc and [protein-only→BH PrPSc] infected bank voles.

Profiles of vacuolation scores of animals inoculated with either M109 cofactor recPrPSc (orange squares) or [protein-only→BH PrPSc] (blue circles). Mean values ± SEM are shown. N = 6 for all measurements except for [protein-only→BH PrPSc] cerebellum and pons, where N = 3.

Fig 5

doi: https://doi.org/10.1371/journal.ppat.1007662.g005