Roles of GP33, a guinea pig cytomegalovirus-encoded G protein-coupled receptor homolog, in cellular signaling, viral growth and inflammation in vitro and in vivo
Fig 9
Pathological findings in r33- and Δ33-infected dams at 3 weeks p.i.
(A) Images of the lungs obtained from the dams infected with r33 (upper row) or Δ33 (lower row), which are described in the legend for Fig 8, are shown in the order of abnormalities in appearance from most severe to mildest. (B) Low and high magnifications of the HE staining of sections prepared from the lungs of the dams infected with r33 or Δ33. Asterisks and arrows indicate infiltration of inflammatory cells and alveolar hemorrhage, respectively. (C) Average number of lesions observed in two sections prepared from each of the dams infected with r33 (open circles) or Δ33 (closed circles). Means and SEMs are shown. (D) Relationship between visible lesion scores on the surface of the lungs determined blindly as described in the Method section and the average number of lesions per cut section. Each circle indicates a lung from each dam.