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Roles of GP33, a guinea pig cytomegalovirus-encoded G protein-coupled receptor homolog, in cellular signaling, viral growth and inflammation in vitro and in vivo

Fig 4

Viral loads in organs after infection of normal animals.

Female 4-week-old guinea pigs (Hartley) were infected i.p. with r33 (open circles) or Δ33 (closed circles) at a low dose (n = 8 each, 1x106 IUs/animal) (A) and at a high dose (n = 4 each, 2x107 IUs/animal) (B). GPCMV genome copies per 106 cells of the indicated organs obtained at 1 week after the infection are plotted. Means and SEMs are shown.

Fig 4

doi: https://doi.org/10.1371/journal.ppat.1007487.g004