Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques
Fig 5
Mtb infection results in granuloma formation and in some instances lymph node effacement.
A. Examples of gross pathology of thoracic lymph nodes from cynomolgus macaques that are minimally involved (left), with focal granuloma (middle) and severely effaced (right). The yellow arrow is pointing to a granuloma. B. Examples of microscopic histopathology of cynomolgus macaque lymph nodes that are not involved (left), with focal granuloma (middle) and severely effaced (right). The arrows are pointing to granulomas.