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Mucosal immunoglobulins protect the olfactory organ of teleost fish against parasitic infection

Fig 6

Increases of IgT+ B cells and IgT concentration in the olfactory organ of trout infected with Ich.

Percentage of IgT+ and IgM+ B cells in NALT (A) and head kidney (B) leukocytes of uninfected control fish, infected fish and survivor fish measured by flow cytometric analysis (n = 12 per group). Concentration of IgT, IgM and IgD in nasal mucus (C) and serum (D) of control, infected and survivor fish (n = 12 per group). *P < 0.05, **P < 0.01 and ***P < 0.001 (one–way ANOVA with Bonferroni correction). Data are representative of at least three independent experiments (mean and s.e.m.). Anova, analysis of variance.

Fig 6

doi: https://doi.org/10.1371/journal.ppat.1007251.g006