Metabotropic glutamate receptor subtype 2 is a cellular receptor for rabies virus
Fig 5
The mGluR2 ectodomain soluble protein (mGluR2-GST) protects mice from lethal challenges in a dose-dependent manner.
mGluR2-GST neutralized the infectivity of GX/09 street virus and protected mice from lethal virus challenges via intramuscular (A) or intracerebral (B) inoculation. The Log-rank (Mantel-Cox) test was used to analyze the statistical difference between the survival rates of the challenged mice. *, p<0.05. **, p<0.01.