Metabotropic glutamate receptor subtype 2 is a cellular receptor for rabies virus
Fig 4
The mGluR2 ectodomain soluble protein (mGluR2-GST) neutralizes the infectivity of RABV in a dose-dependent manner.
mGluR2-GST neutralized ERA-eGFP infection of HEK293 cells (A), SK cells (B), N2a cells (C), and mPN cells (D), and neutralized VSV∆G-ERAG-eGFP infection of HEK293 cells (E) but failed to neutralize VSV-eGFP infection of HEK293 cells (F). A one-way ANOVA was used for the statistical analysis. *, p<0.05. **, p<0.01. ***, p<0.001.