ESCRT machinery components are required for Orthobunyavirus particle production in Golgi compartments
Fig 2
OROV recruits Golgi complex and TGN proteins to its assembly site.
HeLa cells were infected with OROV and fixed after 0 h (A-D) or 24 h p.i. (F-I). Golgi complex and TGN proteins (Giantin and TGN46, respectively) were co-immunostained with OROV proteins and analyzed by confocal microscopy. Bars = 10 μm. (E and J) Insets representing the boxed areas of A-D and F-I, respectively. Bars = 2 μm.