Biphasic zinc compartmentalisation in a human fungal pathogen
Fig 12
Relationship between Zrc1, zincosomes and zinc tolerance.
(A) Cells were challenged with potentially toxic zinc (1 mM), stained with zinquin and fluorescence determined. P < 0.0001 compared to wild type and revertant. (B) Micrographs of cells treated as in A. Note that zrc1Δ is highly defective for zincosome formation in response to 1 mM ZnSO4 –a condition under which wild type, but not zrc1Δ cells can grow (S7 Fig).