TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition
Fig 2
Differential scanning fluorimetry thermal stability profiles of purified TRIM5α proteins.
(A) Comparison of CC-L2, CC-L2-SPRY, and SPRY constructs. (B) Effect of model-based mutations in context CC-L2. (C) Effect of model-based mutations in context of the restriction-competent TRIM5-21R protein.