Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma
Fig 5
Effect of HIF-1α knockdown on the expression of KSHV miRNAs.
(A) Level of primary miRNA transcript as measured by RT-qPCR and normalized to 18S mRNA. (B) Levels of mature miRNAs measured using taqman assays and normalized to that of RNU43 miRNA. Error bars represent standard deviations from at least 3 independent experiments. Statistically significant differences between shScr and shHIF-1 cells are indicated. *P ≤0.05 (2-tailed t-test).