HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes
Fig 13
Correlations of epitope variant susceptibilities to different CTLs targeting SL9, KF11, or KK10 epitopes.
The ΔRE values are compared between CTLs targeting targeting each epitope. Shaded areas indicate ΔRE≥0.7 for one or both CTLs, and red filled symbols indicate those with RE-CTL≥-0.5. Epitope variants that were not detected in the virus libraries (non-replicating) were excluded.