The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing
Fig 5
Abundance and localization of spliceosomal factors during DENV infection.
(A) Western blots showing the levels of splicing proteins CD2BP2, DDX23, EFTUD2, SNRNP40 or SF3A2 and STAT2 used as a control, at 48 h post-infection. (B) Nuclear localization of CD2BP2 or DDX23 and NS5 in DENV infected or mock infected cells. (C) Determination of relative abundance of U2, U4, U5, and U6 snRNAs in DENV infected or mock A549 and Huh-7 cells.