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A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans

Fig 5

Promiscuity of HLA restrictions.

Number of epitopes identified (left y-axis) and the corresponding number of restricting HLA alleles per epitope (x-axis). Percentage of epitopes (right y-axis) restricted by ≥ indicated number of HLA alleles. All restrictions identified (open bars and circles). Restrictions in epitopes tested in ≥2 subjects (black bars and squares).

Fig 5

doi: https://doi.org/10.1371/journal.ppat.1005760.g005