Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins
Fig 5
Suppression of MFN-triggered mitochondrial hyperfusion can be attributed to cleavage by DENV protease.
Confocal microscopy of A549 cells cotransfected with Flag-tagged DENV protease and the indicated MFN constructs for 24 h. Arrows indicate the cells expressing both Flag-tagged DENV protease and HA-tagged MFN. Green: anti-HA; magenta: anti-Flag; red: MitoTracker; blue: DAPI.