RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium
Fig 6
Relative intra-macrophage expression of Salmonella transcription factors and selected target genes.
The expression of individual genes is shown as fold change, intra-macrophage versus ESP. Transcription factors are shown in bold. Target genes controlled by individual transcription factors are shown in the same row (A and C). Expression of transcription factors that regulate SPI2-related genes (A). The regulation of SPI1 genes is controlled by a hierarchy, and the transcription factors are depicted as co-regulators, with their combined target genes (B). Relative expression of 13 metabolic systems (C). Relative expression of up-regulated alternative sigma factors and transcription factors that control oxidative stress, and iron and zinc homeostasis (D). ǂNo dedicated transcription factor for glucose metabolism was assigned.