RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium
Fig 5
The intra-macrophage expression of Salmonella effector genes.
(A) A comparison of absolute expression levels of different S. Typhimurium effector genes within macrophages (Dataset 4 in S1 Table) and in 20 in vitro infection-related conditions [17]. The heatmap colours represent the absolute expression levels (log10 TPM values) based on the colour bar, ranging from TPM values of 49 to 706. (B) The relative expression levels (macrophage versus ESP) of each gene are defined in the colour bar to the right. The genes prgH and ssaG are included to show the SPI1-like and SPI2-like patterns of expression, respectively. The T3SS-independent genes were described by Kidwai et al. (2013) [108].