Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs
Fig 5
Filovirus GP cross-reactivity of 40G1 and 2D8.
(A) Reactivity of 40G1 and 2D8 mAbs to GP antigens determined by ELISA at 5μg/ml. SUDV, Sudan virus; BDBV, Bundibugyo virus; RESTV, Reston virus. (B) Binding curves determined by ELISA with mAb serial dilutions starting at 20μg/ml. Note that MARV GPΔmuc, MARV GPcl, and EBOV GPcl curves overlay in both graphs.