HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission
Fig 2
Dynamics on recrudescence in nine patients enrolled in Panobinostat trial (reference [8]).
(A) The trajectory of viral load of individual patients after ART-interruption. Dashed line indicates threshold of detection (20 copies ml-1) (B) the ‘survival curve’ of patients without detectable virus. The frequency of recrudescence is equivalent to one initiation of viral replication occurring every 7.6 days. (C) growth rate of virus after detection is not significantly correlated with time to recrudescence (p = 0.9).