Macrophage-Derived Human Resistin Is Induced in Multiple Helminth Infections and Promotes Inflammatory Monocytes and Increased Parasite Burden
Figure 7
hRetnTg+ mice are more susceptible to Nb infection.
(A-B) hRetnTg+ mice (black bars) and control hRetnTg− mice (white bars) were infected with 500 L3 Nb worms followed by parasitology analysis by fecal egg counts (A) or adult parasite numbers in the intestine at day 9 (B). Data (mean ± SEM, n = 4–6 per group) are representative of three separate experiments. (C) Serum hResistin concentration in hRetnTg+ mice is positively correlated with Nb worms at day 7 post-infection (n = 12).