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Macrophage-Derived Human Resistin Is Induced in Multiple Helminth Infections and Promotes Inflammatory Monocytes and Increased Parasite Burden

Figure 5

hResistin recruits inflammatory monocytes.

(A-B) Naïve BL/6 mice were treated with recombinant human resistin (500 ng) followed by flow cytometry analysis of CD115+ Ly6C+ inflammatory monocytes (A) and real-time PCR analysis of PEC RNA (B). Data (mean ± SEM, n = 3 per group) are representative of two separate experiments.

Figure 5

doi: https://doi.org/10.1371/journal.ppat.1004579.g005