Macrophage-Derived Human Resistin Is Induced in Multiple Helminth Infections and Promotes Inflammatory Monocytes and Increased Parasite Burden
Figure 2
Monocytes, neutrophils and alveolar macrophages express hResistin in Nb-infected lungs.
(A) Gating strategy for sorted lung cells from Nb-infected mice for CD11b+Ly6C+ monocytes, SiglecF+CD11c− eosinophils, CD11b+Ly6G+ neutrophils, and CD11c+F4/80+ alveolar macrophages and corresponding H&E stained cytospins. (B) Sorted cells were recovered for RNA and analyzed for hRetn by real-time PCR. Data (mean ± SEM, n = 3–4 per group) are representative of three separate experiments.