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P47phox−/− Mice Are Compromised in Expansion and Activation of CD8+ T Cells and Susceptible to Trypanosoma cruzi Infection

Figure 4

Histological analysis of inflammatory infiltrate in T. cruzi-infected p47phox−/− mice.

Shown are representative images of H&E staining (blue: nuclear, pink: muscle/cytoplasm/keratin) of skeletal muscle sections from WT (panels a–d) and p47phox−/− (panels e–h) mice infected with T. cruzi (2000 parasites/mouse), and harvested at day 7 (a&e), 14 (b&f), 21 (c&g), and 30 (d&h) post-infection. H&E stained images from normal mice are shown as insets in panels a and e (magnification: 40×).

Figure 4

doi: https://doi.org/10.1371/journal.ppat.1004516.g004