ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence
Figure 5
SrbB is a transcriptional regulator of genes involved in carbon metabolism, lipid metabolism, and heme biosynthesis.
The FungiFun2 web server was utilized to assign FunCat and gene ontology enrichment in genes with transcript levels increased or decreased 4 fold in ΔsrbB compared to the wild type strain. Statistically significant (P≤0.05) FunCat categories are presented at the respective time points in hypoxia.