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Rabies Virus Hijacks and Accelerates the p75NTR Retrograde Axonal Transport Machinery

Figure 9

Suggested model.

In order to arrive at the cell body and subsequently the CNS, rabies virus hijacks a fast route using the p75NTR endosomal pathway. In a p75NTR dependent path, RABV manipulates the axonal transport machinery to migrate faster to the cell body. An alternative, slower path, may involve alternative RABV receptors.

Figure 9

doi: https://doi.org/10.1371/journal.ppat.1004348.g009