Israeli Acute Paralysis Virus: Epidemiology, Pathogenesis and Implications for Honey Bee Health
Figure 8
IAPV-encoded putative suppressor of RNAi.
(A) Highly conserved octamer sequences identified in dicistroviruses. A putative viral suppressor of RNAi (VSR) is presumably located upstream of DvExNPGP. The cleavage site between the glycine and proline is marked by an arrow. (B) Quantitative analysis of the effects of silencing putative VSR on IAPV replication. The amount of negative stranded RNA of IAPV was measured by RT-qPCR, normalized to the corresponding β-actin in the same sample. The data shown represent the mean value for three separate experiments. Error bars represent the range of fold change.