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Israeli Acute Paralysis Virus: Epidemiology, Pathogenesis and Implications for Honey Bee Health

Figure 6

Regulated molecules that are involved in host metabolism and immunity.

The figure illustrates a network predicted by Ingenuity Pathway Analysis that is centered by viral infection and associated with molecules involved in host energy metabolism and immunity. Solid and dashed connecting lines indicate the presence of direct and indirect interactions, respectively. Nodes indicate input of genes into the pathway analysis and the different symbols indicate gene functions (Legend in bottom left). The intensity of the node color-(red) indicates the degree of up-regulation while the intensity of the node color-(green) indicates the degree of down-regulation. The numbers shown in each node indicates the fold change in response to IAPV infection.

Figure 6

doi: https://doi.org/10.1371/journal.ppat.1004261.g006