Lytic Gene Expression Is Frequent in HSV-1 Latent Infection and Correlates with the Engagement of a Cell-Intrinsic Transcriptional Response
Figure 5
Single cell gene expression profiling reveals the transcriptional response of infected neurons towards latent HSV.
(A) Principal components (PC) analysis of 48 cellular genes in single Ntrk1+neurons – uninfected, YFP− and YFP+. (B) PC analysis on Ntrk1+YFP+ neurons – YFP− versus uninfected. All data are from the main single cell gene expression dataset.