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Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G In Vivo

Figure 6

Expression of A3A and A3G in BMDCs restrict incoming murine retroviruses.

A) Infection of BMDCs with M-MLV. RT-qPCR analysis of genomic DNA with M-MLV-specific primers, normalized to GAPDH. B) MMTV infection of BMDCs with MMTV. RT-qPCR analysis of genomic DNA with MMTV-specific primers, normalized to GAPDH. Shown are the results of 2 independent experiments (open bars, expt.1; closed bars, expt. 2) with 3 technical replicates in each experiment. Error bars (standard deviation) and p values were calculated for each experiment. *, p≤.01 based on one-way ANOVA.

Figure 6

doi: https://doi.org/10.1371/journal.ppat.1004145.g006