A Human Lung Xenograft Mouse Model of Nipah Virus Infection
Figure 5
Cell tropism of Nipah virus in human lung xenografts.
Lung sections were stained by immunofluorescent detection of Nipah virus nucleoprotein (red), CD31 (green) and nucleus (blue) as described in Experimental Procedures. (A) Human lung showing focal area of Nipah virus distinct from pulmonary vasculature on day 3 post infection (10× magnification). (B) CD31 positive endothelium of pulmonary vasculature is positive for Nipah virus antigen (40× magnification). Data are representative from 3 animals per time point.