Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation
Figure 7
Chitin dampens LPS induced inflammation in vivo.
C57BL/6 mice were injected intraperitoneal with saline, chitin, LPS or chitin and LPS in combination. Infiltrating immune cells and cytokine production were analysed after 4 h (A and D), 24 h (B and E) and 4 days (C and F). Data are presented as mean values ± SEM, n = 5 mice per group, *p<0.05, **p<0.01.