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Emergence of Azole-Resistant Aspergillus fumigatus Strains due to Agricultural Azole Use Creates an Increasing Threat to Human Health

Figure 2

A global map depicting geographic distribution of multi-triazole-resistant clinical (red) and environmental (green) Aspergillus fumigatus strains carrying the TR34/L98H (circle) and the TR46/Y121F/T289A mutations (square).

Countrywide prevalence rates (%) of A. fumigatus carrying TR34/L98H are presented excepting the United Kingdom, where overall azole resistance is illustrated. The percent in parentheses denotes environmental prevalence rates.

Figure 2

doi: https://doi.org/10.1371/journal.ppat.1003633.g002