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Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

Figure 2

The gene uge3 (Afu3g07910) encodes a UDP-glucose-4-epimerase and is regulated by both MedA and StuA.

(A) Genes found to be differentially regulated in both ΔmedA and ΔstuA strains by microarray analysis. (B) Expression of uge3, measured by real-time RT-PCR in the indicated strains after 18 h growth. Results indicate the mean expression level from at least three independent experiments ± standard error. * indicates a significantly reduced uge3 mRNA levels as compared with Af293 strain, p<0.05 by factor ANOVA.

Figure 2

doi: https://doi.org/10.1371/journal.ppat.1003575.g002