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Malaria Parasite-Synthesized Heme Is Essential in the Mosquito and Liver Stages and Complements Host Heme in the Blood Stages of Infection

Figure 5

Ookinete formation in the midgut of P.berghei-infected (WT and KOs) mosquitoes.

(A) Quantification of ookinetes formed in vitro using gametocyte cultures. The data represent three independent experiments; P>0.05. (B) Ookinetes formed in vitro and stained with Giemsa reagent. Scale bar: 5 µm. (C) Quantification of ookinetes formed in vivo. (D) Ookinetes formed in vivo and stained with Giemsa reagent. Scale bar: 5 µm. The in vivo data are from 30 mosquitoes from 3 different batches; P>0.05.

Figure 5

doi: https://doi.org/10.1371/journal.ppat.1003522.g005