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Hepatitis B Virus Induces IL-23 Production in Antigen Presenting Cells and Causes Liver Damage via the IL-23/IL-17 Axis

Figure 5

In situ infiltration of IL-23 and IL-17 is significantly correlated with liver injury.

Correlations were analyzed between IL-23 or IL-17 and either plasma log10 HBV loads (copies/mL), serum ALT levels (U/L), HBsAg (IU/mL; concentration above 104), IL-8, or TNF-α. Solid line indicates a linear growth trend. r is the correlation coefficient. P-values are shown.

Figure 5

doi: https://doi.org/10.1371/journal.ppat.1003410.g005