The Escherichia coli Phosphotyrosine Proteome Relates to Core Pathways and Virulence
Figure 2
Definition of E. coli tyrosine phosphorylation site motifs.
(A–E) Probability logos of significantly enriched phosphotyrosine site motifs extracted from 512 unique pTyr sites by aligning peptide sequences comprising 12 residues surrounding the phosphorylated tyrosine residue using Motif-X (p value<0.001). Site motif consensus sequences with variable residues indicated as x and the number of unique sites comprising each motif are indicated. (F) Sequence logos of the general residue representation surrounding the phosphorylated tyrosine residue from the 512 unique sites with residues above the midline being overrepresented and those below underrepresented constructed using Phophosite logo generator.