Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII
Figure 5
Motility (%) generated by CamKII gene knockdown, female and male worms incubated without or with praziquantel for up to 72 h.
Motility % is presented on the left y-axis while the corresponding p-value is presented on the right y-axis. For both sexes, knockdown resulted in no significant changes in mobility without praziquantel treatment. Panel A: Female worms, Panel B: Male parasite without praziquantel treatment. However for both sexes, knockdown leads to less motile worms in the presence of praziquantel. Panel C: Female worms, Panel D: Male parasite with praziquantel treatment. Error bars (SEM) was shown in the figure every 4 h after been treated with or without praziquantel.