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Prophage Induction Is Enhanced and Required for Renal Disease and Lethality in an EHEC Mouse Model

Figure 2

Induction and lysis following mytomycin C treatment.

Aliquots of EDL933 and the cIind1 derivative untreated and treated with 2 µg/ml of mitomycin C were incubated with shaking at 37°. Ind: (+) EDL933, inducible, (−) EDL933cIind1 (K11349), not inducible. Mitomycin C: (+) treated, (−) untreated. Vertical arrow indicates time mitomycin C added.

Figure 2

doi: https://doi.org/10.1371/journal.ppat.1003236.g002