A Heparan-Dependent Herpesvirus Targets the Olfactory Neuroepithelium for Host Entry
Figure 7
Neuroepithelial binding by virion glycoproteins.
The virion HS binding proteins gp70 and gH/gL were expressed as IgG Fc fusions and used to stain neuroepithelial and respiratory epithelial sections from 1 week old naive mice. α-tubulin staining was used to identify the neuronal cilia. The zoomed image shows the boxed region of the merge. Colocalisation appears yellow. Similar results were obtained with 3 mice. The arrows show apical epithelial staining by gHgL-Fc.